Causes of LQTS

Acquired Causes:

Metabolic disorders

Hypokalemia

Hypomagnesemia

Starvation

Anorexia nervosa

Liquid protein diets

Hypothyroidism

Bradyarrhythmias

Sinus node dysfunction

Mitral valve prolapse

Myocardial ischemia or infarction

Intracranial disease

HIV infection

Hypothermia

Drugs:

Anitarrhythmics

Quinidine

Procainamide

Disopyramide

Amiodarone

Sotalol

Antimicrobials

Erythromycin

Clarithromycin

azithromycin

gatifloxacin

levofloxacin

moxifloxacin

mefloquine

Antihistamines

Terfenadine

Astemizole

Psychotropics

Thioridazine

Phenothiazines

Butyrophenones

Tricyclics or Tetracyclics

Haloperidol

SSRI’s

Risperidone

Others

Methadone

Diuretics (via low K+)

Cisapride

Domperidone

Droperidol

Protease Inhibitors

Cocaine

MDMA overdose

Ecstacy overdose